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Consortium for Functional Glycomics
The Consortium for Functional Glycomics (CFG) is a large research initiative funded in 2001 by a glue grant from the National Institute of General Medical Sciences (NIGMS) to “define paradigms by which protein-carbohydrate interactions mediate cell communication”.〔NIGMS press release: http://www.nigms.nih.gov/News/Results/Paulson.htm〕 To achieve this goal, the CFG studies the functions of:
* the three major classes of mammalian glycan-binding proteins (GBPs): C-type lectin, galectin, and SIGLEC
* immune receptors that bind carbohydrates: CD1, T cell receptor, and anti-carbohydrate antibodies
* GBPs of microorganisms that bind to host cell glycans as receptors.
The CFG comprises eight core facilities and 500+ (participating investigators ) that work together to develop (resources and services ) and make them available to the scientific community free of charge. The data generated by these resources are captured in (databases ) accessible through the (Functional Glycomics Gateway ), a web resource maintained through a partnership between the CFG and Nature Publishing Group.
==Organization==
The CFG is composed of three main components: the Participating Investigators, the Cores, and the Steering Committee.
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